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Expedited gene delivery for osteochondral defect repair in a rabbit knee model: A one-year investigation

OBJECTIVE: To evaluate a single-step, gene-based procedure for repairing osteochondral lesions. DESIGN: Osteochondral lesions were created in the patellar groove of skeletally mature rabbits. Autologous bone marrow aspirates were mixed with adenovirus vectors carrying cDNA encoding green fluorescent...

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Detalles Bibliográficos
Autores principales: Nagelli, Christopher V., De La Vega, Rodolfo E., Coenen, Michael, De Padilla, Consuelo Lopez, Panos, Joseph A., Tovar, Alejandro, Müller, Sebastian A., Evans, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635382/
https://www.ncbi.nlm.nih.gov/pubmed/36338933
http://dx.doi.org/10.1016/j.ocarto.2022.100257