Sorafenib-Entrapped, Self-Assembled Pullulan–Stearic Acid Biopolymer-Derived Drug Delivery System to PLC/PRF/5 Hepatocellular Carcinoma Model

PURPOSE: This study aimed to design a prototypic drug delivery system (DDS) made of an amphiphilic, pullulan (Pull)-derived biodegradable polymer for targeting the asialoglycoprotein receptor (ASGPR) overexpressed in HCC. Stearic acid (SA) was conjugated to increase the hydrophobicity of pullulan (P...

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Detalles Bibliográficos
Autores principales: Chirayil, Teena Jacob, Kumar, G S Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635392/
https://www.ncbi.nlm.nih.gov/pubmed/36340185
http://dx.doi.org/10.2147/IJN.S377354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635392/
https://www.ncbi.nlm.nih.gov/pubmed/36340185
http://dx.doi.org/10.2147/IJN.S377354

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