TCR mimic compounds for pHLA targeting with high potency modalities in oncology

pHLA complexes represent the largest class of cell surface markers on cancer cells, making them attractive for targeted cancer therapies. Adoptive cell therapies expressing TCRs that recognize tumor specific pHLAs take advantage of the unique selectivity and avidity of TCR: pHLA interactions. More r...

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Detalles Bibliográficos
Autores principales: Gerber, Hans-Peter, Presta, Leonard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635445/
https://www.ncbi.nlm.nih.gov/pubmed/36338746
http://dx.doi.org/10.3389/fonc.2022.1027548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635445/
https://www.ncbi.nlm.nih.gov/pubmed/36338746
http://dx.doi.org/10.3389/fonc.2022.1027548

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