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Clinical impact of soluble Neuropilin-1 in ovarian cancer patients and its association with its circulating ligands of the HGF/c-MET axis

BACKGROUND: Neuropilin (NRP) is a transmembrane protein, which has been shown to be a pro-angiogenic mediator and implicated as a potential driver of cancer progression. NRP-1 up-regulation in ovarian cancer tissue predicts poor prognosis. However, the clinical relevance of the soluble form of NRP-1...

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Detalles Bibliográficos
Autores principales: Klotz, Daniel Martin, Kuhlmann, Jan Dominik, Link, Theresa, Goeckenjan, Maren, Hofbauer, Lorenz C., Göbel, Andy, Rachner, Tilman D., Wimberger, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635484/
https://www.ncbi.nlm.nih.gov/pubmed/36338759
http://dx.doi.org/10.3389/fonc.2022.974885