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Tbc1d10c is a selective, constitutive suppressor of the CD8 T-cell anti-tumor response
Cancer immunotherapy approaches target signaling pathways that are highly synonymous between CD4 and CD8 T-cell subsets and, therefore, often stimulate nonspecific lymphocyte activation, resulting in cytotoxicity to otherwise healthy tissue. The goal of our study was to identify intrinsic modulators...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635554/ https://www.ncbi.nlm.nih.gov/pubmed/36338148 http://dx.doi.org/10.1080/2162402X.2022.2141011 |