Tbc1d10c is a selective, constitutive suppressor of the CD8 T-cell anti-tumor response

Cancer immunotherapy approaches target signaling pathways that are highly synonymous between CD4 and CD8 T-cell subsets and, therefore, often stimulate nonspecific lymphocyte activation, resulting in cytotoxicity to otherwise healthy tissue. The goal of our study was to identify intrinsic modulators...

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Detalles Bibliográficos
Autores principales: Cohen, Adrienne O., Woo, Seung-Hyun, Zhang, Junya, Cho, Jiyoon, Ruiz, Marlon E., Gong, Jianli, Du, Rong, Yarygina, Olga, Jafri, Danya Z., Bachelor, Michael A., Finlayson, Michael O., Soni, Rajesh K., Hayden, Matthew S., Owens, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635554/
https://www.ncbi.nlm.nih.gov/pubmed/36338148
http://dx.doi.org/10.1080/2162402X.2022.2141011

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