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Extracellular matrix regulation of stress response genes during larval development in Caenorhabditis elegans
Mutation or loss of 6 extracellular matrix collagen genes disrupts annular furrows in adult C. elegans cuticles, causes a wide “Dumpy” body morphology, and activates osmotic, detoxification, and antimicrobial defense genes. High environmental osmolarity reduces internal turgor pressure, physically d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635657/ https://www.ncbi.nlm.nih.gov/pubmed/36000892 http://dx.doi.org/10.1093/g3journal/jkac221 |