Purifying selection enduringly acts on the sequence evolution of highly expressed proteins in Escherichia coli

The evolutionary speed of a protein sequence is constrained by its expression level, with highly expressed proteins evolving relatively slowly. This negative correlation between expression levels and evolutionary rates (known as the E–R anticorrelation) has already been widely observed in past macro...

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Detalles Bibliográficos
Autores principales: Shibai, Atsushi, Kotani, Hazuki, Sakata, Natsue, Furusawa, Chikara, Tsuru, Saburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635659/
https://www.ncbi.nlm.nih.gov/pubmed/36073932
http://dx.doi.org/10.1093/g3journal/jkac235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635659/
https://www.ncbi.nlm.nih.gov/pubmed/36073932
http://dx.doi.org/10.1093/g3journal/jkac235

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