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Analyses of mutational patterns induced by formaldehyde and acetaldehyde reveal similarity to a common mutational signature

Formaldehyde and acetaldehyde are reactive small molecules produced endogenously in cells as well as being environmental contaminants. Both of these small aldehydes are classified as human carcinogens, since they are known to damage DNA and exposure is linked to cancer incidence. However, the mutage...

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Detalles Bibliográficos
Autores principales: Thapa, Mahanish J, Fabros, Reena M, Alasmar, Salma, Chan, Kin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635668/
https://www.ncbi.nlm.nih.gov/pubmed/36073936
http://dx.doi.org/10.1093/g3journal/jkac238