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Robust linear DNA degradation supports replication–initiation-defective mutants in Escherichia coli
RecBCD helicase/nuclease supports replication fork progress via recombinational repair or linear DNA degradation, explaining recBC mutant synthetic lethality with replication elongation defects. Since replication initiation defects leave chromosomes without replication forks, these should be insensi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635670/ https://www.ncbi.nlm.nih.gov/pubmed/36165702 http://dx.doi.org/10.1093/g3journal/jkac228 |