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Robust linear DNA degradation supports replication–initiation-defective mutants in Escherichia coli

RecBCD helicase/nuclease supports replication fork progress via recombinational repair or linear DNA degradation, explaining recBC mutant synthetic lethality with replication elongation defects. Since replication initiation defects leave chromosomes without replication forks, these should be insensi...

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Detalles Bibliográficos
Autores principales: Rao, T V Pritha, Kuzminov, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635670/
https://www.ncbi.nlm.nih.gov/pubmed/36165702
http://dx.doi.org/10.1093/g3journal/jkac228

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