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Fractional transit compartment model for describing drug delayed response to tumors using Mittag-Leffler distribution on age-structured PKPD model

The response of a cell population is often delayed relative to drug injection, and individual cells in a population of cells have a specific age distribution. The application of transit compartment models (TCMs) is a common approach for describing this delay. In this paper, we propose a TCM in which...

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Detalles Bibliográficos
Autores principales: Byun, Jong Hyuk, Roh, Yunil, Yoon, In-Soo, Kim, Kwang Su, Jung, Il Hyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635704/
https://www.ncbi.nlm.nih.gov/pubmed/36331932
http://dx.doi.org/10.1371/journal.pone.0276654