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Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study

Plasma and liver SerpinB1 levels are elevated in mice with insulin resistance and promote β-cell proliferation in human islets. We measured serum SerpinB1 levels in Japanese subjects with or without type 2 diabetes (T2DM). We enrolled 12 normal glucose tolerance (NGT) and 51 T2DM subjects. There was...

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Detalles Bibliográficos
Autores principales: Kyohara, Mayu, Miyashita, Daisuke, Inoue, Ryota, Nishiyama, Kuniyuki, Tsuno, Takahiro, Okuyama, Tomoko, Togashi, Yu, Terauchi, Yasuo, Shirakawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635728/
https://www.ncbi.nlm.nih.gov/pubmed/36331940
http://dx.doi.org/10.1371/journal.pone.0276915