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In vitro inhibition of acetylcholinesterase activity by yellow field pea (Pisum sativum) protein-derived peptides as revealed by kinetics and molecular docking

Compounds with structural similarities to the neurotransmitter (acetylcholine) are mostly used to inhibit the activity of acetylcholinesterase (AChE) in Alzheimer’s disease (AD) therapy. However, the existing drugs only alleviate symptoms of moderate to mild conditions and come with side effects; he...

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Detalles Bibliográficos
Autores principales: Asen, Nancy D., Okagu, Ogadimma D., Udenigwe, Chibuike C., Aluko, Rotimi E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635817/
https://www.ncbi.nlm.nih.gov/pubmed/36337665
http://dx.doi.org/10.3389/fnut.2022.1021893