Cargando…

The HUSH complex controls brain architecture and protocadherin fidelity

The HUSH (human silencing hub) complex contains the H3K9me3 binding protein M-phase phosphoprotein 8 (MPP8) and recruits the histone methyltransferase SETDB1 as well as Microrchidia CW-type zinc finger protein 2 (MORC2). Functional and mechanistic studies of the HUSH complex have hitherto been cente...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagelkruys, Astrid, Horrer, Marion, Taubenschmid-Stowers, Jasmin, Kavirayani, Anoop, Novatchkova, Maria, Orthofer, Michael, Pai, Tsung-Pin, Cikes, Domagoj, Zhuk, Sergei, Balmaña, Meritxell, Esk, Christopher, Koglgruber, Rubina, Moeseneder, Paul, Lazovic, Jelena, Zopf, Lydia M., Cronin, Shane J.F., Elling, Ulrich, Knoblich, Jürgen A., Penninger, Josef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635835/
https://www.ncbi.nlm.nih.gov/pubmed/36332029
http://dx.doi.org/10.1126/sciadv.abo7247