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The HUSH complex controls brain architecture and protocadherin fidelity
The HUSH (human silencing hub) complex contains the H3K9me3 binding protein M-phase phosphoprotein 8 (MPP8) and recruits the histone methyltransferase SETDB1 as well as Microrchidia CW-type zinc finger protein 2 (MORC2). Functional and mechanistic studies of the HUSH complex have hitherto been cente...
Autores principales: | Hagelkruys, Astrid, Horrer, Marion, Taubenschmid-Stowers, Jasmin, Kavirayani, Anoop, Novatchkova, Maria, Orthofer, Michael, Pai, Tsung-Pin, Cikes, Domagoj, Zhuk, Sergei, Balmaña, Meritxell, Esk, Christopher, Koglgruber, Rubina, Moeseneder, Paul, Lazovic, Jelena, Zopf, Lydia M., Cronin, Shane J.F., Elling, Ulrich, Knoblich, Jürgen A., Penninger, Josef M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635835/ https://www.ncbi.nlm.nih.gov/pubmed/36332029 http://dx.doi.org/10.1126/sciadv.abo7247 |
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