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Astrocytic dysfunction induced by ABCA1 deficiency causes optic neuropathy

Astrocyte abnormalities have received great attention for their association with various diseases in the brain but not so much in the eye. Recent independent genome-wide association studies of glaucoma, optic neuropathy characterized by retinal ganglion cell (RGC) degeneration, and vision loss found...

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Detalles Bibliográficos
Autores principales: Shinozaki, Youichi, Leung, Alex, Namekata, Kazuhiko, Saitoh, Sei, Nguyen, Huy Bang, Takeda, Akiko, Danjo, Yosuke, Morizawa, Yosuke M., Shigetomi, Eiji, Sano, Fumikazu, Yoshioka, Nozomu, Takebayashi, Hirohide, Ohno, Nobuhiko, Segawa, Takahiro, Miyake, Kunio, Kashiwagi, Kenji, Harada, Takayuki, Ohnuma, Shin-ichi, Koizumi, Schuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635836/
https://www.ncbi.nlm.nih.gov/pubmed/36332025
http://dx.doi.org/10.1126/sciadv.abq1081