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Antibacterial T6SS effectors with a VRR-Nuc domain are structure-specific nucleases

The type VI secretion system (T6SS) secretes antibacterial effectors into target competitors. Salmonella spp. encode five phylogenetically distinct T6SSs. Here, we characterize the function of the SPI-22 T6SS of Salmonella bongori showing that it has antibacterial activity and identify a group of an...

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Detalles Bibliográficos
Autores principales: Hespanhol, Julia Takuno, Sanchez-Limache, Daniel Enrique, Nicastro, Gianlucca Gonçalves, Mead, Liam, Llontop, Edgar Enrique, Chagas-Santos, Gustavo, Farah, Chuck Shaker, de Souza, Robson Francisco, Galhardo, Rodrigo da Silva, Lovering, Andrew L, Bayer-Santos, Ethel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635880/
https://www.ncbi.nlm.nih.gov/pubmed/36226828
http://dx.doi.org/10.7554/eLife.82437