Cargando…
Antibacterial T6SS effectors with a VRR-Nuc domain are structure-specific nucleases
The type VI secretion system (T6SS) secretes antibacterial effectors into target competitors. Salmonella spp. encode five phylogenetically distinct T6SSs. Here, we characterize the function of the SPI-22 T6SS of Salmonella bongori showing that it has antibacterial activity and identify a group of an...
Autores principales: | Hespanhol, Julia Takuno, Sanchez-Limache, Daniel Enrique, Nicastro, Gianlucca Gonçalves, Mead, Liam, Llontop, Edgar Enrique, Chagas-Santos, Gustavo, Farah, Chuck Shaker, de Souza, Robson Francisco, Galhardo, Rodrigo da Silva, Lovering, Andrew L, Bayer-Santos, Ethel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635880/ https://www.ncbi.nlm.nih.gov/pubmed/36226828 http://dx.doi.org/10.7554/eLife.82437 |
Ejemplares similares
-
Intercepting biological messages: Antibacterial molecules targeting nucleic acids during interbacterial conflicts
por: Hespanhol, Julia Takuno, et al.
Publicado: (2023) -
Regulation of type VI secretion systems at the transcriptional, posttranscriptional and posttranslational level
por: Hespanhol, Julia Takuno, et al.
Publicado: (2023) -
Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity
por: Celma, Louisa, et al.
Publicado: (2017) -
Staphylococcus aureus Nuc2 Is a Functional, Surface-Attached Extracellular Nuclease
por: Kiedrowski, Megan R., et al.
Publicado: (2014) -
The VrrA sRNA controls a stationary phase survival factor Vrp of Vibrio cholerae
por: Sabharwal, Dharmesh, et al.
Publicado: (2015)