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Melatonin exerts anti-fibrinolytic effects by regulating IL-1β-induced changes in uPA, uPAR, and PAI-1 expression/production in human dental pulp cells

Interleukin-1β (IL-1β) is a pro-inflammatory cytokine and its expression is increased in inflamed dental pulp. IL-1β affects plasminogen activation system molecules, which are crucial for tissue inflammation, fibrinolysis, matrix turnover, and cell adhesion and migration. Melatonin, which provides c...

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Detalles Bibliográficos
Autores principales: Chang, Mei-Chi, Zhong, Bor-Hao, Lee, Hui-Na, Chuang, Fu-Hsiung, Lee, Ming-Shu, Chang, Hsiao-Hua, Pan, Yu-Hwa, Jeng, Jiiang-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635917/
http://dx.doi.org/10.38212/2224-6614.3415