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Biological screening of a unique drug library targeting MRGPRX2

BACKGROUND: Allergic drug reaction or drug allergy is an immunologically mediated drug hypersensitivity reaction (DHR). G-protein coupled receptors (GPCRs) are common drug targets and communicate extracellular signals that initiate cellular responses. Recent evidence shows that GPCR MRGPRX2 is of ma...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Limjunyawong, Nathachit, Peng, Qi, Schroeder, John T., Saini, Sarbjit, MacGlashan, Donald, Dong, Xinzhong, Gao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635925/
https://www.ncbi.nlm.nih.gov/pubmed/36341461
http://dx.doi.org/10.3389/fimmu.2022.997389