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Biological screening of a unique drug library targeting MRGPRX2
BACKGROUND: Allergic drug reaction or drug allergy is an immunologically mediated drug hypersensitivity reaction (DHR). G-protein coupled receptors (GPCRs) are common drug targets and communicate extracellular signals that initiate cellular responses. Recent evidence shows that GPCR MRGPRX2 is of ma...
Autores principales: | Yang, Fan, Limjunyawong, Nathachit, Peng, Qi, Schroeder, John T., Saini, Sarbjit, MacGlashan, Donald, Dong, Xinzhong, Gao, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635925/ https://www.ncbi.nlm.nih.gov/pubmed/36341461 http://dx.doi.org/10.3389/fimmu.2022.997389 |
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