Stress-induced glucocorticoid desensitizes adrenoreceptors to gate the neuroendocrine response to somatic stress in male mice

Noradrenergic afferents to hypothalamic corticotropin releasing hormone (CRH) neurons provide a major excitatory drive to the hypothalamic-pituitary-adrenal (HPA) axis via α1 adrenoreceptor activation. Noradrenergic afferents are recruited preferentially by somatic, rather than psychological, stress...

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Detalles Bibliográficos
Autores principales: Jiang, Zhiying, Chen, Chun, Weiss, Grant L., Fu, Xin, Stelly, Claire E., Sweeten, Brook L.W., Tirrell, Parker S., Pursell, India, Stevens, Carly R., Fisher, Marc O., Begley, John C., Harrison, Laura M., Tasker, Jeffrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635929/
https://www.ncbi.nlm.nih.gov/pubmed/36261014
http://dx.doi.org/10.1016/j.celrep.2022.111509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635929/
https://www.ncbi.nlm.nih.gov/pubmed/36261014
http://dx.doi.org/10.1016/j.celrep.2022.111509

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