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Grifolamine A, a novel bis-γ-butyrolactone from Grifola frondosa exerted inhibitory effect on α-glucosidase and their binding interaction: Affinity and molecular dynamics simulation

A novel bis-γ-butyrolactone grifolamine A (1), the first γ-butyrolactone dimer from nature, together with three known γ-butyrolactones (2–4), was isolated from the byproduct from Grifola frondosa polysaccharides preparation process. The structure and stereochemistry of grifolamine A (1) were elucida...

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Detalles Bibliográficos
Autores principales: Chen, Shaodan, Mu, Zhenqiang, Yong, Tianqiao, Gu, Jiangyong, Zhang, Yifan, Gao, Xiong, Xie, Yizhen, Xiao, Chun, Hu, Huiping, Yang, Xiaobing, Li, Xiangmin, Cai, Manjun, Wu, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636034/
https://www.ncbi.nlm.nih.gov/pubmed/36345431
http://dx.doi.org/10.1016/j.crfs.2022.10.026