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Single‐cell and spatial transcriptomics reveal the fibrosis‐related immune landscape of biliary atresia

BACKGROUND: Biliary atresia (BA) is a devastating inflammatory and fibrosing cholangiopathy of neonates with unknown aetiology. We aim to investigate the relationship between these two main characteristics. METHODS: Single‐cell RNA sequencing and spatial transcriptomics were performed on liver sampl...

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Detalles Bibliográficos
Autores principales: Ye, Chunjing, Zhu, Jiajie, Wang, Junfeng, Chen, Deqian, Meng, Lingdu, Zhan, Yong, Yang, Ran, He, Shiwei, Li, Zifeng, Dai, Shuyang, Li, Yi, Sun, Song, Shen, Zhen, Huang, Yanlei, Dong, Rui, Chen, Gong, Zheng, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636046/
https://www.ncbi.nlm.nih.gov/pubmed/36333281
http://dx.doi.org/10.1002/ctm2.1070