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Transcriptional regulation and chromatin dynamics at DNA double-strand breaks

In eukaryotic cells, DNA damage can occur at any time and at any chromatin locus, including loci at which active transcription is taking place. DNA double-strand breaks affect chromatin integrity and elicit a DNA damage response to facilitate repair of the DNA lesion. Actively transcribed genes near...

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Detalles Bibliográficos
Autores principales: Min, Sunwoo, Ji, Jae-Hoon, Heo, Yungyeong, Cho, Hyeseong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636152/
https://www.ncbi.nlm.nih.gov/pubmed/36229590
http://dx.doi.org/10.1038/s12276-022-00862-5