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Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal
Hippocampal place cells support reward-related spatial memories by forming a cognitive map that over-represents reward locations. The strength of these memories is modulated by the extent of reward expectation during encoding. However, the circuit mechanisms underlying this modulation are unclear. H...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636178/ https://www.ncbi.nlm.nih.gov/pubmed/36333323 http://dx.doi.org/10.1038/s41467-022-34465-5 |