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CD8(+) T cell differentiation status correlates with the feasibility of sustained unresponsiveness following oral immunotherapy

While food allergy oral immunotherapy (OIT) can provide safe and effective desensitization (DS), the immune mechanisms underlying development of sustained unresponsiveness (SU) following a period of avoidance are largely unknown. Here, we compare high dimensional phenotypes of innate and adaptive im...

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Detalles Bibliográficos
Autores principales: Kaushik, Abhinav, Dunham, Diane, Han, Xiaorui, Do, Evan, Andorf, Sandra, Gupta, Sheena, Fernandes, Andrea, Kost, Laurie Elizabeth, Sindher, Sayantani B., Yu, Wong, Tsai, Mindy, Tibshirani, Robert, Boyd, Scott D., Desai, Manisha, Maecker, Holden T., Galli, Stephen J., Chinthrajah, R. Sharon, DeKruyff, Rosemarie H., Manohar, Monali, Nadeau, Kari C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636180/
https://www.ncbi.nlm.nih.gov/pubmed/36333296
http://dx.doi.org/10.1038/s41467-022-34222-8