A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages

Itaconate is a newly discovered endogenous metabolite promoting an anti-inflammatory program during innate immune response, but the precise mechanisms underlying its effect remains poorly understood owing primarily to the limitations of available itaconate-monitoring techniques. Here, we develop and...

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Detalles Bibliográficos
Autores principales: Sun, Pengkai, Zhang, Zhenxing, Wang, Bin, Liu, Caiyun, Chen, Chao, Liu, Ping, Li, Xinjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636186/
https://www.ncbi.nlm.nih.gov/pubmed/36333306
http://dx.doi.org/10.1038/s41467-022-34306-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636186/
https://www.ncbi.nlm.nih.gov/pubmed/36333306
http://dx.doi.org/10.1038/s41467-022-34306-5

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