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A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages
Itaconate is a newly discovered endogenous metabolite promoting an anti-inflammatory program during innate immune response, but the precise mechanisms underlying its effect remains poorly understood owing primarily to the limitations of available itaconate-monitoring techniques. Here, we develop and...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636186/ https://www.ncbi.nlm.nih.gov/pubmed/36333306 http://dx.doi.org/10.1038/s41467-022-34306-5 |