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Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence

The present study investigates the possible therapeutic effects of human mesenchymal stem cell-derived secretome on morphine dependence and relapse. This was studied in a new model of chronic voluntary morphine intake in Wistar rats which shows classic signs of morphine intoxication and a severe nal...

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Detalles Bibliográficos
Autores principales: Quintanilla, María Elena, Quezada, Mauricio, Morales, Paola, Berríos-Cárcamo, Pablo, Santapau, Daniela, Ezquer, Marcelo, Herrera-Marschitz, Mario, Israel, Yedy, Ezquer, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636200/
https://www.ncbi.nlm.nih.gov/pubmed/36333316
http://dx.doi.org/10.1038/s41398-022-02225-0