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Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence
The present study investigates the possible therapeutic effects of human mesenchymal stem cell-derived secretome on morphine dependence and relapse. This was studied in a new model of chronic voluntary morphine intake in Wistar rats which shows classic signs of morphine intoxication and a severe nal...
Autores principales: | Quintanilla, María Elena, Quezada, Mauricio, Morales, Paola, Berríos-Cárcamo, Pablo, Santapau, Daniela, Ezquer, Marcelo, Herrera-Marschitz, Mario, Israel, Yedy, Ezquer, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636200/ https://www.ncbi.nlm.nih.gov/pubmed/36333316 http://dx.doi.org/10.1038/s41398-022-02225-0 |
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