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SET/PP2A signaling regulates macrophage positioning in hypoxic tumor regions by amplifying chemotactic responses

Tumor-associated macrophages (TAMs) are one of the main cellular components in the tumor microenvironment (TME). In many types of solid tumors, TAMs tend to accumulate in hypoxic areas and are intimately related to poor patient prognosis. However, the underlying mechanisms by which TAMs infiltrate h...

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Detalles Bibliográficos
Autores principales: Zhang, Shaolong, Zhou, Jingping, Shang, Pengzhao, Zhao, Guomeng, Wang, Anlei, Mao, Jinlei, Tao, Yuhang, Chen, Ziyi, Wang, Xuehao, Guo, Changying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636225/
https://www.ncbi.nlm.nih.gov/pubmed/36224346
http://dx.doi.org/10.1038/s12276-022-00867-0