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SET/PP2A signaling regulates macrophage positioning in hypoxic tumor regions by amplifying chemotactic responses
Tumor-associated macrophages (TAMs) are one of the main cellular components in the tumor microenvironment (TME). In many types of solid tumors, TAMs tend to accumulate in hypoxic areas and are intimately related to poor patient prognosis. However, the underlying mechanisms by which TAMs infiltrate h...
Autores principales: | Zhang, Shaolong, Zhou, Jingping, Shang, Pengzhao, Zhao, Guomeng, Wang, Anlei, Mao, Jinlei, Tao, Yuhang, Chen, Ziyi, Wang, Xuehao, Guo, Changying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636225/ https://www.ncbi.nlm.nih.gov/pubmed/36224346 http://dx.doi.org/10.1038/s12276-022-00867-0 |
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