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Spatial analysis of the glioblastoma proteome reveals specific molecular signatures and markers of survival

Molecular heterogeneity is a key feature of glioblastoma that impedes patient stratification and leads to large discrepancies in mean patient survival. Here, we analyze a cohort of 96 glioblastoma patients with survival ranging from a few months to over 4 years. 46 tumors are analyzed by mass spectr...

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Detalles Bibliográficos
Autores principales: Duhamel, Marie, Drelich, Lauranne, Wisztorski, Maxence, Aboulouard, Soulaimane, Gimeno, Jean-Pascal, Ogrinc, Nina, Devos, Patrick, Cardon, Tristan, Weller, Michael, Escande, Fabienne, Zairi, Fahed, Maurage, Claude-Alain, Le Rhun, Émilie, Fournier, Isabelle, Salzet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636229/
https://www.ncbi.nlm.nih.gov/pubmed/36333286
http://dx.doi.org/10.1038/s41467-022-34208-6