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Predicting the efficacy of opioid sequestration by intravenous lipid emulsion using biologically relevant in vitro models of drug distribution

Intravenous lipid emulsions (ILE), among other uses, are utilized in the treatment of poisonings caused by lipophilic substances. The body of evidence regarding the benefits of this treatment is growing but information about opioids-ILE interaction is still very scarce. In this work, the impact of I...

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Detalles Bibliográficos
Autores principales: Tikhomirov, Marta, Jajor, Paweł, Śniegocki, Tomasz, Poźniak, Błażej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636243/
https://www.ncbi.nlm.nih.gov/pubmed/36333363
http://dx.doi.org/10.1038/s41598-022-21790-4