CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy

Store-operated Ca(2+)-entry is a cellular mechanism that governs the replenishment of intracellular stores of Ca(2+) upon depletion caused by the opening of intracellular Ca(2+)-channels. Gain-of-function mutations of the 2 key proteins of store-operated Ca(2+)-entry, STIM1 and ORAI1, are associated...

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Detalles Bibliográficos
Autores principales: Cordero-Sanchez, Celia, Pessolano, Emanuela, Riva, Beatrice, Vismara, Mauro, Trivigno, Silvia Maria Grazia, Clemente, Nausicaa, Aprile, Silvio, Ruffinatti, Federico Alessandro, Portararo, Paola, Filigheddu, Nicoletta, Zaggia, Ivan, Bhela, Irene P., Serafini, Marta, Pirali, Tracey, Colombo, Mario P., Torti, Mauro, Sangaletti, Sabina, Bertoni, Alessandra, Genazzani, Armando A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636319/
https://www.ncbi.nlm.nih.gov/pubmed/35696753
http://dx.doi.org/10.1182/bloodadvances.2021006378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636319/
https://www.ncbi.nlm.nih.gov/pubmed/35696753
http://dx.doi.org/10.1182/bloodadvances.2021006378

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