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CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy
Store-operated Ca(2+)-entry is a cellular mechanism that governs the replenishment of intracellular stores of Ca(2+) upon depletion caused by the opening of intracellular Ca(2+)-channels. Gain-of-function mutations of the 2 key proteins of store-operated Ca(2+)-entry, STIM1 and ORAI1, are associated...
Autores principales: | Cordero-Sanchez, Celia, Pessolano, Emanuela, Riva, Beatrice, Vismara, Mauro, Trivigno, Silvia Maria Grazia, Clemente, Nausicaa, Aprile, Silvio, Ruffinatti, Federico Alessandro, Portararo, Paola, Filigheddu, Nicoletta, Zaggia, Ivan, Bhela, Irene P., Serafini, Marta, Pirali, Tracey, Colombo, Mario P., Torti, Mauro, Sangaletti, Sabina, Bertoni, Alessandra, Genazzani, Armando A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636319/ https://www.ncbi.nlm.nih.gov/pubmed/35696753 http://dx.doi.org/10.1182/bloodadvances.2021006378 |
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