Refining the migration and engraftment of short-term and long-term HSCs by enhancing homing-specific adhesion mechanisms

In contrast to the short-term (ST) CD34(+) stem cells, studies have suggested that long-term (LT) hematopoietic stem cells (HSCs) found in the CD34(−) stem cell pool have trouble migrating and engrafting when introduced through IV. To understand why these deficiencies exist, we set out to fully eluc...

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Detalles Bibliográficos
Autores principales: Al-Amoodi, Asma S., Li, Yanyan, Al-Ghuneim, Arwa, Allehaibi, Hanaa, Isaioglou, Ioannis, Esau, Luke E., AbuSamra, Dina B., Merzaban, Jasmeen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636332/
https://www.ncbi.nlm.nih.gov/pubmed/35764498
http://dx.doi.org/10.1182/bloodadvances.2022007465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636332/
https://www.ncbi.nlm.nih.gov/pubmed/35764498
http://dx.doi.org/10.1182/bloodadvances.2022007465

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