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Refining the migration and engraftment of short-term and long-term HSCs by enhancing homing-specific adhesion mechanisms
In contrast to the short-term (ST) CD34(+) stem cells, studies have suggested that long-term (LT) hematopoietic stem cells (HSCs) found in the CD34(−) stem cell pool have trouble migrating and engrafting when introduced through IV. To understand why these deficiencies exist, we set out to fully eluc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society of Hematology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636332/ https://www.ncbi.nlm.nih.gov/pubmed/35764498 http://dx.doi.org/10.1182/bloodadvances.2022007465 |