CD44–fibrinogen binding promotes bleeding in acute promyelocytic leukemia by in situ fibrin(ogen) deposition

Early hemorrhagic death is still the main obstacle for the successful treatment of acute promyelocytic leukemia (APL). However, the mechanisms underlying hemostatic perturbations in APL have not been fully elucidated. Here, we report that CD44 on the membrane of APL blasts and NB4 cells ligated boun...

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Detalles Bibliográficos
Autores principales: Wang, Chunxu, Wang, Yufeng, Zuo, Nan, Fang, Shaohong, Shi, Jialan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636334/
https://www.ncbi.nlm.nih.gov/pubmed/35511736
http://dx.doi.org/10.1182/bloodadvances.2022006980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636334/
https://www.ncbi.nlm.nih.gov/pubmed/35511736
http://dx.doi.org/10.1182/bloodadvances.2022006980

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