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Blockade of FGF2/FGFR2 partially overcomes bone marrow mesenchymal stromal cells mediated progression of T-cell acute lymphoblastic leukaemia

The development of acute lymphoblastic leuakemia (ALL) is partly attributed to the effects of bone marrow (BM) microenvironment, especially mesenchymal stromal cells (MSCs), which interact bilaterally with leukaemia cells, leading to ALL progression. In order to find MSCs-based microenvironment targ...

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Detalles Bibliográficos
Autores principales: Tian, Chen, Li, Yueyang, Wang, Lina, Si, Junqi, Zheng, Yaxin, Kang, Junnan, Wang, Yafei, You, M. James, Zheng, Guoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636388/
https://www.ncbi.nlm.nih.gov/pubmed/36333298
http://dx.doi.org/10.1038/s41419-022-05377-5