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T-cell counts in peripheral blood at leukapheresis predict responses to subsequent CAR-T cell therapy

Prediction of responses to chimeric antigen receptor (CAR)-T cell therapies is essential to maximize their therapeutic efficacy for diffuse large B-cell lymphoma (DLBCL). While several tumor-intrinsic risk factors of resistance and/or early relapse have been identified, clinically useful markers tha...

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Detalles Bibliográficos
Autores principales: Wada, Fumiya, Jo, Tomoyasu, Arai, Yasuyuki, Kitawaki, Toshio, Mizumoto, Chisaki, Kanda, Junya, Nishikori, Momoko, Yamashita, Kouhei, Nagao, Miki, Takaori-Kondo, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636390/
https://www.ncbi.nlm.nih.gov/pubmed/36333521
http://dx.doi.org/10.1038/s41598-022-23589-9