The identification of TCF1(+) progenitor exhausted T cells in THRLBCL may predict a better response to PD-1/PD-L1 blockade

T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a rare and aggressive variant of diffuse large B-cell lymphoma (DLBCL) that usually affects young to middle-aged patients, with disseminated disease at presentation. The tumor microenvironment (TME) plays a key role in THRLBCL due to its pecu...

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Detalles Bibliográficos
Autores principales: Tabanelli, Valentina, Melle, Federica, Motta, Giovanna, Mazzara, Saveria, Fabbri, Marco, Agostinelli, Claudio, Calleri, Angelica, Del Corvo, Marcello, Fiori, Stefano, Lorenzini, Daniele, Cesano, Alessandra, Chiappella, Annalisa, Vitolo, Umberto, Derenzini, Enrico, Griffin, Gabriel K., Rodig, Scott J., Vanazzi, Anna, Sabattini, Elena, Tarella, Corrado, Sapienza, Maria Rosaria, Pileri, Stefano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636403/
https://www.ncbi.nlm.nih.gov/pubmed/35767735
http://dx.doi.org/10.1182/bloodadvances.2022007046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636403/
https://www.ncbi.nlm.nih.gov/pubmed/35767735
http://dx.doi.org/10.1182/bloodadvances.2022007046

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