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Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment

Cancer-associated fibroblasts (CAFs) are the predominant components of the tumor microenvironment (TME) and influence cancer hallmarks, but without systematic investigation on their ubiquitous characteristics across different cancer types. Here, we perform pan-cancer analysis on 226 samples across 1...

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Detalles Bibliográficos
Autores principales: Luo, Han, Xia, Xuyang, Huang, Li-Bin, An, Hyunsu, Cao, Minyuan, Kim, Gyeong Dae, Chen, Hai-Ning, Zhang, Wei-Han, Shu, Yang, Kong, Xiangyu, Ren, Zhixiang, Li, Pei-Heng, Liu, Yang, Tang, Huairong, Sun, Ronghao, Li, Chao, Bai, Bing, Jia, Weiguo, Liu, Yi, Zhang, Wei, Yang, Li, Peng, Yong, Dai, Lunzhi, Hu, Hongbo, Jiang, Yong, Hu, Yiguo, Zhu, Jingqiang, Jiang, Hong, Li, Zhihui, Caulin, Carlos, Park, Jihwan, Xu, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636408/
https://www.ncbi.nlm.nih.gov/pubmed/36333338
http://dx.doi.org/10.1038/s41467-022-34395-2