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In silico investigation and surmounting of Lipopolysaccharide barrier in Gram-Negative Bacteria: How far has molecular dynamics Come?

Lipopolysaccharide (LPS), a main component of the outer membrane of Gram-negative bacteria, has crucial implications on both antibiotic resistance and the overstimulation of the host innate immune system. Fighting against these global concerns calls for the molecular understanding of the barrier fun...

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Detalles Bibliográficos
Autores principales: González-Fernández, Cristina, Bringas, Eugenio, Oostenbrink, Chris, Ortiz, Inmaculada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636410/
https://www.ncbi.nlm.nih.gov/pubmed/36382192
http://dx.doi.org/10.1016/j.csbj.2022.10.039