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Circular RNA CREBBP modulates cartilage degradation by activating the Smad1/5 pathway through the TGFβ2/ALK1 axis

Osteoarthritis, characterized by articular cartilage degradation, is the leading cause of chronic disability in older adults. Studies have indicated that circular RNAs are crucial regulators of chondrocyte development and are involved in the progression of osteoarthritis. In this study, we investiga...

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Detalles Bibliográficos
Autores principales: Xu, Yiyang, Mao, Guping, Long, Dianbo, Deng, Zengfa, Xin, Ruobin, Zhang, Ziji, Xue, Ting, Liao, Weiming, Xu, Jie, Kang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636424/
https://www.ncbi.nlm.nih.gov/pubmed/36224344
http://dx.doi.org/10.1038/s12276-022-00865-2