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Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2

The relaxin/insulin-like family peptide receptor 2 (RXFP2) belongs to the family of class A G-protein coupled receptors (GPCRs) and it is the only known target for the insulin-like factor 3 peptide (INSL3). The importance of this ligand-receptor pair in the development of the gubernacular ligament d...

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Detalles Bibliográficos
Autores principales: Esteban-Lopez, Maria, Wilson, Kenneth J., Myhr, Courtney, Kaftanovskaya, Elena M., Henderson, Mark J., Southall, Noel T., Xu, Xin, Wang, Amy, Hu, Xin, Barnaeva, Elena, Ye, Wenjuan, George, Emmett R., Sherrill, John T., Ferrer, Marc, Morello, Roy, Agoulnik, Irina U., Marugan, Juan J., Agoulnik, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636434/
https://www.ncbi.nlm.nih.gov/pubmed/36333465
http://dx.doi.org/10.1038/s42003-022-04143-9