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Sivelestat improves clinical outcomes and decreases ventilator-associated lung injury in children with acute respiratory distress syndrome: a retrospective cohort study

BACKGROUND: Sivelestat, a neutrophil elastase inhibitor, is a selective and targeted therapy for acute respiratory distress syndrome (ARDS) in adults; and it is also reported to apply to children with ARDS. However, there is little evidence of its efficacy in children. METHODS: This study recruited...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Wang, Min, Zhang, Hua, Wang, Ying, Du, Yanqiang, Guo, Zhangyan, Ma, Le, Zhou, Yong, Zhang, Huiping, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636449/
https://www.ncbi.nlm.nih.gov/pubmed/36345446
http://dx.doi.org/10.21037/tp-22-441