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Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility

OBJECTIVE: Adipose tissue thermogenesis has been suggested as a new therapeutic target to promote energy metabolism for obesity and metabolic disease. Cold-inducible thermogenic adipocytes, called beige adipocytes, have attracted significant attention for their potent anti-obesity activity in adult...

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Detalles Bibliográficos
Autores principales: So, Jisun, Taleb, Solaema, Wann, Jamie, Strobel, Olivia, Kim, Kyungchan, Roh, Hyun Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636484/
https://www.ncbi.nlm.nih.gov/pubmed/36273781
http://dx.doi.org/10.1016/j.molmet.2022.101619